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Genetics, plainly.

Explainers and deep-dives on the science behind your DNA report — methylation, neurotransmitters, polygenic risk, and what to actually do about them.

Editorial illustration of a central DNA helix surrounded by lifestyle icons — sleep, caffeine, exercise, vitamin D, food, hydration

snps explained

Genetic Health Optimization: DNA-Informed Lifestyle

Generic optimization advice ignores your genetics. Here is how to use your raw DNA file to inform sleep, diet, training, and supplements — with the caveats that matter.

May 1, 2026 · 6 min read

Editorial illustration of four service icons representing DNA analysis services

snps explained

GenoSight vs Promethease vs SelfDecode vs Nebula 2026

Compare GenoSight, Promethease, SelfDecode, and Nebula on raw DNA upload support, price, AI synthesis, citations, privacy, and clinician-ready reports.

May 1, 2026 · 9 min read

Editorial illustration of a DNA helix dispersing as data particles into an AI brain icon

snps explained

How AI Reads Your DNA: Inside the Synthesis Pipeline

AI doesn't replace genetic science — it removes the bottleneck between raw variant calls and personal context. Here's exactly how an AI genetic report is built.

May 1, 2026 · 6 min read

Editorial illustration of a long DNA helix with a single highlighted center segment, the rest fading subtly

clinical genetics

Limits of Consumer DNA Testing: What It Can't Tell You

Consumer DNA tests look at a few hundred thousand positions, not your full genome. Here is what they reliably catch, what they miss, and when clinical-grade testing matters.

May 1, 2026 · 6 min read

Editorial illustration of a DNA file inside a transparent shield with a padlock, surrounded by soft botanical accents

clinical genetics

Raw DNA Data Privacy: What Happens After You Upload

Genetic data is the most personal data you have. Here is exactly what GenoSight does with your raw DNA file — encryption, access, what is sent to AI, and deletion.

May 1, 2026 · 6 min read

Editorial illustration of a DNA helix flowing from a raw file icon into a structured report card

snps explained

How GenoSight Turns Raw DNA Into Reports

See how GenoSight turns a raw 23andMe, AncestryDNA, or MyHeritage file into an AI-synthesized educational health report.

May 1, 2026 · 5 min read

Editorial illustration of an open report book surrounded by floating health-context icons

snps explained

What's in a GenoSight Report: The 6 Health Domains

A GenoSight report reasons about your genetics against six health profile domains. Here is exactly what each domain captures and why it changes the report output.

May 1, 2026 · 5 min read

Editorial illustration of a central DNA helix with four primary-source icons — book, database, microscope, document — in a constellation

clinical genetics

GenoSight Data Sources: ClinVar, PharmGKB, GWAS, PubMed

Every GenoSight finding traces back to a primary source. Here is what ClinVar, GWAS Catalog, PharmGKB, and PubMed are — and why the source choice matters for trust.

May 1, 2026 · 6 min read

Diagram of the methylation cycle showing folate, B12, B6, and B2 as cofactors

MTHFR

Methylation vitamins: a genetics-first guide to methylated B-complex supplements

Methylated B-vitamins help if you carry an MTHFR variant. Here's how to read your 23andMe genotype to decide if 5-MTHF is worth the extra cost.

April 30, 2026 · 7 min read

methylation

MTHFR Explained: What the Most-Hyped Variant Actually Means

rs1801133 affects how your body activates folate. Here's what 'compound heterozygous' really tells you about supplementation choices.

April 29, 2026 · 3 min read