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MTHFR

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Diagram of the methylation cycle showing folate, B12, B6, and B2 as cofactors

MTHFR

Methylation vitamins: a genetics-first guide to methylated B-complex supplements

Methylated B-vitamins help if you carry an MTHFR variant. Here's how to read your 23andMe genotype to decide if 5-MTHF is worth the extra cost.

April 30, 2026 · 7 min read