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Methylation

Methylation is the biochemical process of attaching a methyl group to another molecule. Your body runs it billions of times per second for DNA repair, neurotransmitter synthesis, and detoxification. Variants in MTHFR, MTR, MTRR, COMT, and CBS change how well this cycle runs — and whether methylated B-vitamins are worth the extra cost.

3 articles

Computer screen comparing genotype calls with separately measured CpG methylation status

methylation

CpG DNA Methylation and Raw DNA Files Explained

Learn what CpG DNA methylation means, how it differs from inherited genotype data, and why consumer raw DNA files need separate context.

October 6, 2026 · 5 min read

Raw DNA table flowing into methylation-pathway genes and an educational report, with a note that it is not a methylation-level assay

methylation

DNA Methylation Genes: What Raw DNA Can Show

Learn which methylation-related genes may appear in a consumer raw DNA file, what those variants can and cannot tell you, and when lab testing matters.

October 2, 2026 · 7 min read

methylation

MTHFR Explained: What the Most-Hyped Variant Actually Means

rs1801133 affects how your body activates folate. Here's what 'compound heterozygous' really tells you about supplementation choices.

April 29, 2026 · 3 min read