23andMe COMT raw data
Does 23andMe test COMT?
Sometimes the answer means a named 23andMe report. Sometimes it means whether your raw data contains COMT rs4680 Val158Met. GenoSight helps with the second path: checking a compatible raw genotype file and turning supported findings into a readable educational report.
Two questions get mixed together
Report availability and raw-marker coverage are separate.
- Named 23andMe report availability can change
- Raw data may include COMT rs4680
- GenoSight checks compatible raw genotype files
- Educational only, not clinical confirmation
The careful answer
COMT has enough online shorthand that wording matters. Start by separating a consumer report, raw data lookup, and clinical testing into three different buckets.
If you mean a 23andMe report
23andMe product menus and regional availability can change. A named consumer report is different from checking whether raw data contains COMT rsIDs.
If you mean raw data
23andMe raw data can be searched by gene, rsID, or position. The COMT marker people usually ask about is rs4680 Val158Met, but coverage can vary.
If you mean medical testing
Consumer raw DNA is informational. A clinical medication, mood, pain, or methylation question belongs with a qualified clinician and appropriate testing.
Source boundaries
23andMe describes raw data as informational, and its raw-data help center explains searching by gene, marker, or position. GenoSight keeps the same boundary: raw DNA is useful context, not a diagnosis or treatment plan.
23andMe and COMT questions
Does 23andMe include COMT?
It depends what you mean. 23andMe raw data can often be searched for COMT rsIDs such as rs4680, but coverage and report availability can vary by product and chip version.
Which COMT marker should I search for in 23andMe raw data?
The common marker is rs4680, also called COMT Val158Met. Some tools also look at nearby COMT context markers, but rs4680 is the usual starting point.
Can GenoSight read my 23andMe raw data for COMT?
Yes. GenoSight can analyze a compatible 23andMe raw genotype file and frame COMT alongside MTHFR, caffeine and stimulant context, sleep, stress, goals, and report caveats. It is educational only.
Can I check COMT before uploading a file?
Yes. GenoSight has a browser-only COMT raw data checker that runs locally and shows marker presence plus raw genotype strings without interpreting them.