Free COMT raw data checker
Check COMT markers in your raw DNA file.
Drop in a 23andMe, AncestryDNA, or MyHeritage raw genotype file to see whether it contains COMT rs4680 Val158Met and selected nearby COMT context markers. The scan runs locally in your browser and shows raw file values only.
Want to see the output first? Use the synthetic marker example.
This checker reports marker presence and the raw genotype string only. It does not classify alleles, diagnose conditions, recommend supplements, or send your genotype data to GenoSight.
What this checker looks for
The goal is narrow on purpose: answer whether selected COMT raw-data markers are present before anyone tries to interpret them.
COMT rs4680 / Val158Met
Searches for rs4680, the common COMT Val158Met marker people usually mean when they ask about slow COMT or COMT raw data.
COMT context markers
Also checks selected adjacent COMT rsIDs when present. These are context markers, not standalone supplement rules.
Full report path
GenoSight can put COMT into broader methylation, caffeine, stimulant, stress, sleep, and goal context after marker lookup.
Why the checker avoids interpretation
COMT Val158Met is easy to flatten into internet shorthand. A raw genotype string can be strand-dependent, chip-dependent, and incomplete. GenoSight keeps this free page to marker presence and handles broader context inside educational reports.
See rs4680 marker contextGuardrails
Useful without pretending to be clinical.
- Runs locally in your browser
- Shows raw genotype strings only
- Does not use warrior, worrier, good, bad, or normal labels
- Does not recommend methyl donors, supplements, or medication changes
COMT raw data checker questions
Can I check COMT from 23andMe raw data?
Often, yes. This checker looks for selected COMT rsIDs such as rs4680 in compatible raw genotype files. Coverage can vary by provider and chip version.
Can I check COMT from AncestryDNA or MyHeritage raw data?
Yes, when the file is a compatible raw genotype download and includes the relevant COMT markers. Missing coverage should not be treated as a medical negative result.
Does this page tell me whether I have slow COMT?
No. It only shows whether selected COMT markers are present and what raw genotype string appears in the file. Labels such as slow COMT are simplified shorthand and can be misleading without context.
What should I run after checking COMT markers?
For COMT questions, Detox & Methylation is the most direct first report. Mental Wellbeing and Personality can also include COMT context when relevant.
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