MyHeritage methylation analysis
Turn MyHeritage raw DNA data into a careful methylation report.
GenoSight can use a compatible MyHeritage raw genotype file to review selected MTHFR, COMT, folate, and B-vitamin context in an educational Detox and Methylation report. It does not measure methylation levels or prescribe supplements.
Good fit when
You want health context from a genealogy file.
You already downloaded a compatible MyHeritage raw DNA data file
You want MTHFR and COMT context from a genealogy-focused test file
You want citations, caveats, and a PDF-ready educational report
You understand this does not measure methylation levels or diagnose a condition
Workflow
Start with the file, then slow down the interpretation.
Download the raw file
Use the Manage DNA kits download from your MyHeritage account. GenoSight needs the raw tab-delimited genotype file, not an ethnicity estimate, match list, screenshot, FASTQ, BAM, or VCF file.
Check marker coverage
Coverage can vary by chip version. The local MTHFR and COMT checker can show whether common markers such as rs1801133, rs1801131, and rs4680 appear in your file.
Run Detox and Methylation
The report frames MTHFR, COMT, folate, B-vitamin, and adjacent context with uncertainty instead of turning raw genotype strings into supplement instructions.
Methylation genes are not methylation measurements.
A raw genotype file can show inherited variants that may be relevant to folate, B-vitamin, and catecholamine discussions. It cannot show your current methylation status, homocysteine, nutrient levels, symptoms, or medication context.
What the MyHeritage raw data file gives you
A tab-delimited marker table created from a MyHeritage DNA test, separate from ethnicity estimates, Genetic Groups, and DNA matches.
What GenoSight adds
Plain-language educational synthesis, source context, report caveats, PDFs, and findings-grounded chat on paid plans.
What neither replaces
Clinical methylation testing, homocysteine labs, folate or B12 labs, diagnosis, treatment, prescribing, or personalized supplement dosing.
GenoSight pricing
Try the methylation report before paying.
New accounts receive 250 credits with no card required. Choose monthly when you already know you want more reports, PDFs, regeneration, and findings-grounded chat.
Start free
$0
250 signup credits
Usually enough to run the first Detox and Methylation report from your raw DNA file before paying.
Start freeMonthly
$11.99
1,500 credits per month
Choose this when methylation is the first topic and you also want PDFs, regeneration, other reports, and chat.
Choose monthlyYearly
$99.99
18,000 credits per year
Best when you expect to work through the broader health-report library after the methylation report.
Choose yearlySource notes
Public references used for this page.
MyHeritage raw DNA download
Explains Manage DNA kits download steps, email-link timing, 24-hour link validity, device limits, and third-party compatibility caveats.
MyHeritage raw DNA interpretation
Explains the tab-delimited raw data file, rsID column, chromosome, position, allele columns, SNPs, indels, and forward-strand notes.
MedlinePlus Genetics: MTHFR
Consumer genetics reference for MTHFR and folate-pathway context.
NCBI Gene: COMT
Reference entry for catechol-O-methyltransferase and catecholamine O-methylation context.
FAQ
MyHeritage methylation analysis questions.
Can GenoSight do methylation analysis from MyHeritage raw DNA data?
Yes, if the file is a compatible MyHeritage raw genotype export. GenoSight can generate an educational Detox and Methylation report that frames selected methylation-related variants such as MTHFR and COMT with caveats and source context.
Does this measure my DNA methylation levels?
No. A MyHeritage raw genotype file is not an epigenetic methylation assay. GenoSight reviews inherited variants and explains related context; it does not measure methylation levels, epigenetic age, or current biochemical status.
Which markers are people usually looking for?
Common searches include MTHFR C677T rs1801133, MTHFR A1298C rs1801131, and COMT Val158Met rs4680. Coverage depends on the raw file and chip version.
Can the report tell me which supplements to take?
No. GenoSight keeps the output educational. Supplement decisions depend on labs, diet, symptoms, medications, pregnancy status, and clinician guidance, not one raw DNA marker.