Local caffeine marker checker
Check CYP1A2 and ADORA2A markers in your raw DNA file.
Drop in a 23andMe, AncestryDNA, or MyHeritage raw genotype file to see whether it contains selected caffeine-related rsIDs. The scan runs locally in your browser and shows raw file values only.
Want to see the output first? Use the synthetic marker example.
This checker reports marker presence and the raw genotype string only. It does not classify you as a fast or slow caffeine metabolizer, recommend caffeine intake, diagnose conditions, or send your genotype data to GenoSight.
First check coverage. Then interpret carefully.
People often search for caffeine genes before knowing whether their raw file contains the relevant markers. This page answers that smaller question without turning a SNP into advice.
CYP1A2 rs762551
Looks for the common CYP1A2 marker many people mean when they ask about caffeine metabolism from 23andMe, AncestryDNA, or MyHeritage raw data.
ADORA2A rs5751876
Looks for an adenosine-receptor marker studied around caffeine-related arousal, anxiety, and sleep response in compatible provider raw files.
ADORA2A rs2298383
Looks for another ADORA2A marker sometimes reviewed with caffeine sensitivity and sleep context.
Why this page avoids fast/slow labels
Caffeine response is not just CYP1A2. Sleep quality, stress response, blood pressure, medications, pregnancy status, and actual caffeine timing all matter. GenoSight keeps this free checker narrow, then handles context in the full educational report.
Open the caffeine sensitivity DNA test guideSee caffeine report contextGuardrails
Useful without pretending to be clinical.
- Shows marker presence and raw genotype strings only
- Does not classify you as fast, slow, sensitive, or insensitive
- Does not recommend a caffeine dose, cutoff time, or medication change
- Does not upload the raw DNA file to GenoSight
Not sure which caffeine markers your provider includes?
Start with the provider-level question, then use the local checker to see what is present in your actual file.
Caffeine raw data questions
Can I check caffeine genes from my 23andMe raw data?
Often, yes. This checker looks for selected rsIDs such as CYP1A2 rs762551 and ADORA2A rs5751876 in a raw genotype file. Coverage can vary by provider and chip version.
Does the checker tell me if I am a slow caffeine metabolizer?
No. The free checker only shows marker presence and raw genotype strings. The full Foods & Drinks report adds broader evidence, habit context, and careful educational framing.
Why avoid interpretation on the free checker?
Caffeine response depends on genotype, sleep, anxiety response, blood pressure, medications, pregnancy status, and actual caffeine habits. A single raw SNP should not become a dosing rule.
What should I run after finding caffeine markers?
For GenoSight, the most direct first report is Foods & Drinks, which fits inside the 250-credit no-card signup grant. Reports remain educational and are not clinical diagnosis.
250 free credits, no card