APOE raw DNA marker
APOE rs7412 in raw DNA data.
rs7412 is the other common APOE marker people search for beside rs429358. GenoSight can check whether your raw DNA file contains it, then keep APOE interpretation separate from the free marker lookup.
Marker pair
rs7412 is usually considered with rs429358.
- Browser-only local marker check
- Raw genotype string only
- Do not interpret rs7412 by itself
- Full report adds caveats before APOE context
rs7412 only makes sense inside the pair.
GenoSight keeps this page focused on the raw marker because the broader APOE conversation can affect how people think about future health, relatives, and insurance decisions.
What rs7412 is
rs7412 is commonly paired with rs429358 when people try to understand APOE e2/e3/e4 context from a raw genotype file.
What a missing marker means
A missing rs7412 call usually means missing raw-data coverage or a file-format issue. It should not be treated as a normal or low-risk medical result.
How GenoSight handles it
The free checker shows only marker presence and raw genotype strings. Full reports add careful context around lipids, cognitive aging, family history, and counseling.
Evidence boundary
Direct-to-consumer APOE interpretation is sensitive and cannot predict whether a person will or will not develop Alzheimer disease. Use raw markers as educational context only.
Provider starting points
If you are checking a specific raw DNA export, start with the matching provider page before interpreting APOE context.
23andMe rs7412
Search a 23andMe raw genotype file for rs7412 with sensitive-result caveats.
Open guideAncestryDNA rs7412
Check AncestryDNA raw data coverage before drawing APOE conclusions.
Open guideMyHeritage rs7412
Look for rs7412 in a MyHeritage raw DNA data file with paired-marker context.
Open guideAPOE rs7412 questions
Can I find APOE rs7412 in my AncestryDNA raw data?
Sometimes, but coverage varies by provider and chip version. Use the browser-only APOE raw data checker to see whether rs7412 is present in your specific file.
Can rs7412 be interpreted without rs429358?
No. APOE context commonly depends on rs7412 plus rs429358, and even then it should be interpreted with source, strand, clinical, and counseling caveats.
Why does GenoSight avoid e-status labels on the free checker?
APOE can be psychologically and practically sensitive. The free checker is intentionally limited to marker lookup so people can decide whether they want broader interpretation.
Which GenoSight report includes rs7412 context?
APOE can appear in Heart Health, Aging & Longevity, and Foods & Drinks when the file and user context support it. New accounts receive 250 free credits with no card required.