Pharmacogenomics from raw DNA
Medication-response context without medication instructions.
GenoSight can surface educational pharmacogenomics context from compatible 23andMe, AncestryDNA, and MyHeritage raw DNA files. Use it as discussion material, not a clinical test or a reason to change medication.
Not a clinical PGx test
Educational context only.
- Do not change medications from GenoSight output
- Consumer raw data can miss clinically important variants
- Prescribing decisions require qualified clinical care
- Useful as preparation for clinician or pharmacist questions
Medication-response context
GenoSight can surface supported medication-response discussion points when a compatible raw DNA file has usable findings.
Evidence-aware caveats
Reports distinguish educational context from prescribing guidance and keep clinical decisions with qualified professionals.
Raw-file limits
Consumer raw DNA files may miss clinically relevant alleles, structural variants, star-allele phasing, and lab-grade confirmation.
What GenoSight can support
Flag supported medication-response discussion points where the raw file has usable data
Point to why a gene-drug topic may be worth discussing with a clinician or pharmacist
Keep medication context beside your health profile instead of treating one marker as a verdict
Provide educational report and chat context on paid plans without sending the raw genotype file to the LLM
What GenoSight cannot do
Tell you to start, stop, switch, or dose a medication
Replace a clinical pharmacogenomic test ordered by a qualified professional
Guarantee full gene coverage, star-allele calling, or companion-diagnostic status from consumer raw data
Interpret emergency, oncology, psychiatric, anticoagulant, or pain-medication decisions without clinical care
Source-aware boundaries
Medication genetics is useful because the limits are explicit.
FDA, CPIC, and PharmGKB resources all point toward the same safe posture: evidence matters, but medication decisions require a health professional and the full clinical picture.
FDA pharmacogenetic associations table
The FDA table explains that genotype may inform therapy in some contexts, while patients should not adjust medications without the prescriber.
Open sourceCPIC guidelines
CPIC creates peer-reviewed gene-drug guidelines for clinicians, and its site says information is not for direct diagnostic use without a health professional.
Open sourcePharmGKB evidence levels
PharmGKB and ClinPGx organize clinical annotations by evidence level, which is useful context but not a substitute for clinical interpretation.
Open sourcePricing path
Start free, then upgrade only if the discussion context helps.
Medication-response context is sensitive. Use the no-card path to check product fit, and only pay for deeper reports, PDFs, and follow-up if the framing is useful.
Free trial
$0
250 signup credits, no card
Use the free path to see whether GenoSight report language is useful before paying for deeper exploration.
Start freeMonthly
Popular$11.99
1,500 credits per month
Best for reviewing findings, PDFs, and report-grounded follow-up questions after the first pass.
Choose monthlyYearly
$99.99
18,000 credits per year
For broader exploration across medication-response context, methylation, nutrition, heart, and related reports.
Choose yearlyLifetime
$229
6,000 credits per month, for life
For people who expect to revisit the same raw DNA file and report library over time.
Choose lifetimePharmacogenomics raw DNA questions
Common questions before using raw DNA data for medication context.
Can GenoSight do pharmacogenomics from 23andMe raw data?
GenoSight can provide educational medication-response discussion context from compatible consumer raw DNA files when supported findings are present. It is not a clinical pharmacogenomic test.
Can I change a medication based on a GenoSight report?
No. Do not start, stop, switch, or dose a medication from GenoSight output. Medication decisions belong with a qualified prescriber who can review clinical testing, labels, history, labs, and current medications.
Why is consumer raw DNA limited for medication response?
Consumer genotype files may not capture every clinically important variant, allele combination, copy-number change, or star-allele call. Missing data can matter more than present markers.
What is the safe use for this page?
Use it as a starting point for understanding why medication-response genetics exists, what GenoSight can surface, and what questions to bring to a clinician or pharmacist.
No medication changes
Use raw DNA as context, not as a prescription.
Start with a compatible file, keep the clinical boundary clear, and bring important medication questions to a qualified professional.